New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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Nanotechnology provides A variety of chances to add to biology. In this article I will present examples in which nanofabrication – the opportunity to make confined constructions with Proportions at will – is applied to look at the biophysics of one molecules and cells. I'll current some illustrations from our lab:
Our team reports bacterial cell division and it is aiming to constitute a ‘base up biology’ in artificial cells that could autonomously divide. Our major curiosity lies in cell division, chromatin composition, and spatial Regulate.
Back in 1991, Sumio Iijima from the NEC Corporation had noted the synthesis of carbon nanotubes. Band construction calculations recommended that these nanotubes could exhibit metallic band conduction. This could be a substantial benefit above the conducting polymers we had explored, which had been, the truth is, disordered semiconductors presenting just variable-selection hopping conductivity.
Our function was swiftly followed up by Other folks, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors made out of solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.
This yielded a breakthrough. Within just only a few months, we ended up capable of evaluate transport by a person one-walled carbon nanotube. According to small-temperature experiments by a brilliant PhD scholar in my group, Sander Tans (now a valued colleague and professor at Delft College of Engineering having an Energetic investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with incredibly long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Microbiology has only been around for the century, considering the fact that we began to analyze micro-organisms more seriously. I thought nanobiology was an suitable phrase, since all molecular biological pertinent interactions happen with the nanoscale: a protein is a number of nanometres in size, DNA is 2 nm thick.’
We use nanofabricated microfluidic constructions to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the elemental role of spatial confinement at the molecular and mobile amount. Our initiatives include things like the next:
He also uncovered time to write down quite a few publications, send out Nearly forty thousand tweets and direct A prosperous analysis team at Delft University of Technological innovation. ‘It doesn’t feel like operate’, he suggests. ‘I’m ceesdekker.net just terribly curious.’
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Right now, we also recognized that it should be feasible to make use of just one semiconducting carbon nanotube to produce a transistor — and we set out to really make it. We stretched particular person semiconducting nanotubes throughout metallic electrodes and employed the underlying silicon substrate as a gate electrode, creating The essential 3-terminal layout of the industry-influence transistor (Fig.
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Cees Dekker is Distinguished University Professor at TU Delft. Skilled being a physicist, he pioneered nanotechnology with a lot of discoveries on carbon nanotubes while in the nineties. Given that 2000, he moved to solitary-molecule biophysics and nanobiology. His present study focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a residing synthetic cell from lifeless molecules. Dekker is an elected member of the KNAW and fellow to the APS as well as IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)